STUDY OF THE BLOOD COAGULATION PROCESS BY MEANS OF THE BIOSPECKLE TECHNIQUE

Abstract

In this work, an experimental approach was used to evaluate the usefulness of the biospeckle technique in the study of the blood coagulation process. Partial thromboplastin times with activator were analyzed in normal plasma, Factor VIII-deficient plasma, and a mixture of both. The results show a correlation between changes in speckle patterns and fibrin mesh formation in normal and pathological samples. Consequently, the biospeckle technique can be a useful tool to evaluate hemostasis and the changes generated in fibrin polymerization in the face of deficiencies or interferences.

Keywords: biospeckle, blood coagulation, THSP, correlation coefficient, signal processing.