THEORETICAL AND COMPUTATIONAL ESTIMATION OF THE STOPPING POWER FOR ELECTRONS AND PROTONS FOR A PAGAT DOSIMETER INFUSED WITH GOLD NANOPARTICLES IN THE ENERGY RANGE OF THERAPEUTIC APPLICATIONS

Authors

  • C. Salinas Domj´an 1 Instituto de F´ısica Enrique Gaviola, IFEG-CONICET, C´ordoba, Argentina 5Laboratorio de Investigaci´on e Instrumentaci´on en F´ısica Aplicada a la Medicina e Im´agenes de Rayos X, LIIFAMIR○x ; Argentina
  • F. Mattea 2 Instituto de Investigaci´on y Desarrollo en Ingenier´ıa de Procesos y Qu´ımica Aplicada, C´ordoba, Argentina 3Departamento de Qu´ımica Org´anica, Facultad de Ciencias Qu´ımicas, UNC, C´ordoba, Argentina 5Laboratorio de Investigaci´on e Instrumentaci´on en F´ısica Aplicada a la Medicina e Im´agenes de Rayos X, LIIFAMIR○x ; Argentina
  • M. Romero 2 Instituto de Investigaci´on y Desarrollo en Ingenier´ıa de Procesos y Qu´ımica Aplicada, C´ordoba, Argentina 3Departamento de Qu´ımica Org´anica, Facultad de Ciencias Qu´ımicas, UNC, C´ordoba, Argentina 5Laboratorio de Investigaci´on e Instrumentaci´on en F´ısica Aplicada a la Medicina e Im´agenes de Rayos X, LIIFAMIR○x ; Argentina
  • I. Scarinci 1 Instituto de F´ısica Enrique Gaviola, IFEG-CONICET, C´ordoba, Argentina 5Laboratorio de Investigaci´on e Instrumentaci´on en F´ısica Aplicada a la Medicina e Im´agenes de Rayos X, LIIFAMIR○x ; Argentina
  • M. Valente 1 Instituto de F´ısica Enrique Gaviola, IFEG-CONICET, C´ordoba, Argentina 4Centro de Excelencia de F´ısica e Ingenier´ıa en Salud - CFIS & Departamento Ciencias F´ısicas, Universidad de La Frontera; Chile 5Laboratorio de Investigaci´on e Instrumentaci´on en F´ısica Aplicada a la Medicina e Im´agenes de Rayos X, LIIFAMIR○x ; Argentina

Abstract

The present work focuses on the behavior of the stopping power of a polymer gel dosimetry system, known
as PAGAT, infused with high atomic number nanoparticles formed by gold, with a 1 % mass concentration.
The study is carried out for different energies of electron and proton beams within ranges of therapeutic
applications, first by theoretical assessment, and then by simulation with Monte Carlo codes: PENELOPE
in the case of electrons, and FLUKA in the case of protons. The results obtained analytically show promising
behavior for gold nanoparticle infused tissue-equivalent systems, while the simulation results show better
correspondence with models that consider the net path traveled, instead of models based on the thickness
of the samples as typically done in experimental determinations.

Published

2024-09-29 — Updated on 2024-09-30

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Medical Physics